Peripheral cholinergic function in humans with chronic fatigue syndrome, Gulf War syndrome and with illness following organophosphate exposure.

Cholinergic autonomic dysfunction in veterans with Gulf War illness: confirmation in a population-based sample.

BACKGROUND The authors of prior small studies raised the hypothesis that symptoms in veterans of the 1991 Gulf War, such as chronic diarrhea, dizziness, fatigue, and sexual dysfunction, are due to cholinergic autonomic dysfunction. OBJECTIVE To perform a confirmatory test of this prestated hypothesis in a larger, representative sample of Gulf War veterans. DESIGN Nested case-control study. ...

Chronic fatigue syndrome following a toxic exposure.

Chronic fatigue syndrome (CFS) is a clinical entity characterized by severe fatigue lasting more than 6 months and other well-defined symptoms. Even though in most CFS cases the etiology is still unknown, sometimes the mode of presentation of the illness implicates the exposure to chemical and/or food toxins as precipitating factors: ciguatera poisoning, sick building syndrome, Gulf War syndrom...

Exercise Challenge in Gulf War Illness Reveals Two Subgroups with Altered Brain Structure and Function

Nearly 30% of the approximately 700,000 military personnel who served in Operation Desert Storm (1990-1991) have developed Gulf War Illness, a condition that presents with symptoms such as cognitive impairment, autonomic dysfunction, debilitating fatigue and chronic widespread pain that implicate the central nervous system. A hallmark complaint of subjects with Gulf War Illness is post-exertion...

Systematic reviews of psychological disorders, multisymptom illness and chronic fatigue syndrome in veterans deployed to the Gulf War, Afghanistan or Iraq War

JP-8 jet fuel exposure and divided attention test performance in 1991 Gulf War veterans.

INTRODUCTION Previous research indicates that a large cohort of veterans from the 1991 Gulf War report polysymptomatic conditions. These syndromes often involve neurocognitive complaints, fatigue, and musculoskeletal symptoms, thus overlapping with civilian illnesses from low levels of environmental chemicals, chronic fatigue syndrome, and fibromyalgia. METHODS To test for time-dependent chan...